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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/23867
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Campo DCValorIdioma
dc.contributor.authorOliveira, Flávia Márcia-
dc.contributor.authorGusmão, Leandro José-
dc.contributor.authorCardoso, Valbert do Nascimento-
dc.contributor.authorRamaldes, Gilson Andrade-
dc.contributor.authorRuiz-de-Souza, Valéria-
dc.date.accessioned2025-11-17T18:42:14Z-
dc.date.available2025-11-17T18:42:14Z-
dc.date.issued2013-08-
dc.identifier.citationOLIVEIRA, F. M. et al. Ethanol affects the absorption and tissue distribution of orally administered antigens in mice. Brazilian Archives of Biology and Technology, Curitiba, v. 56, n. 4, p. 581-586, jul./ago. 2013. Disponível em: https://www.scielo.br/j/babt/a/WS6RK98bxbvGNN7pMT5Hgtz/?lang=en. Acesso em: 17 nov. 2025.pt_BR
dc.identifier.issn1678-4324-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23867-
dc.languageengpt_BR
dc.publisherInstituto de Tecnologia do Paraná - Tecparpt_BR
dc.relation.ispartofBrazilian Archives of Biology and Technologypt_BR
dc.subjectEthanoleng
dc.subjectAbsorptioneng
dc.subjectBiodistributioneng
dc.subjectTechnetiumeng
dc.subjectImmune responseeng
dc.titleEthanol affects the absorption and tissue distribution of orally administered antigens in micept_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)pt_BR
dc.description.resumoThe aim of this work was to evaluate the effects of ethanol on the adsorption and tissue distribution of orally administered antigens in mice. Results showed that ethanol reduced the level of anti-ovalbumin IgA antibodies in intestinal fluid for the mice treated orally with a palmitoyl–ovalbumin conjugate. Ethanol was administered intragastrically to mice at 5 g/kg body weight for 14 days (chronic treatment), or 10 g/kg body weight every 7th day up to 14 days (acute treatment). Thereafter, 99mtechnetium-labeled antigens were administered and lymphoid tissues were collected. Ethanol interfered with the transport of ovalbumin to the liver. Moreover, the transport of palmitoyl–ovalbumin to mesenteric lymph nodes was reduced 6 h after the antigen administration. In conclusion, there was a relationship between the suppression of ethanol-mediated specific local IgA responses and the decreased transport of palmitoyl–ovalbumin to mesenteric lymph nodes.pt_BR
dc.description.localCuritibapt_BR
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