Efeito da terapia fotodinâmica antimicrobiana na redução imediata de compostos sulfurados voláteis

Abstract

The volatile sulfides (CSVs) are linked to bad breath and are submitted to protein degradation promoted by microorganisms of the oral cavity. The dorsum of the tongue is the main branch of the production of CSVs due to the accumulation of lingual saburra. An antimicrobial photodynamic therapy (PDT) is a therapy that promotes bacterial destruction. The aim of this study is to evaluate the immediate effect of antimicrobial photodynamic therapy (TFDa) on the levels of oral CSVs in reduced time of exposure of the laser associated with the lingual scaling. 27 subjects were randomly divided into three groups: G1 treated with mechanical removal of the tongue coating (n = 9), G2 treated with the mechanical removal of the tongue coating, and TFDa (n=9) and G3 treated with TFDa only (n = 9). Measurements of volatile sulfur compounds (CSVs) were performed with the Halimeter® portable device, before and immediately after treatment, in triplicate, and the results were read in parts per billion (ppb). The G1 and G2 were submitted to scraping the tongue divided into 2 sides and 10 strokes were applied on each side. G2 and G3 were submitted to PDT with the apparatus calibrated with wavelength of 660 nm, power of 20 mW, creep of 10 J / cm2 for 20 seconds in 6 different sites in the dorsal region of the tongue in the middle and posterior thirds. The data in ppb were used for intra-group analysis with the Wilcoxon test (α = 0.05) and then transformed into a percentage reduction for analysis between groups with the ANOVA test (α = 0.05). There was a significant reduction in CSV levels in all groups (P <0.05). The Analysis of Variance indicated no significant difference between the groups (P = 0.5929): G1 (28%); G2 (37%); G3 (30%). It was concluded that there was an immediate reduction of CSV levels for all the therapies evaluated. TFDa isolated or associated to the tongue scraper was equivalent to the tongue scraper group when applied in reduced time of laser exposure.