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dc.contributor.authorMaciel, Leonardo Yung dos Santos-
dc.contributor.authorCruz, Kamilla Mayara Lucas da-
dc.contributor.authorAraujo, Ariane Martins de-
dc.contributor.authorSilva, Zak Moreira de Andrade-
dc.contributor.authorBadauê Passos, Daniel-
dc.contributor.authorSantana-Filho, Valter Joviniano-
dc.contributor.authorDeSantana, Josimari Melo-
dc.date.accessioned2026-01-28T19:27:14Z-
dc.date.available2026-01-28T19:27:14Z-
dc.date.issued2014-
dc.identifier.citationMACIEL, L. Y. S. et al. Electroacupuncture reduces hyperalgesia after injections of acidic saline in rats. Evidence-Based Complementary and Alternative Medicine, New York, n. 1, 2014. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2014/485043. Acesso em: 28 jan. 2026.pt_BR
dc.identifier.issn1741-4288-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/24435-
dc.languageengpt_BR
dc.publisherHindawi Publishing Corporationpt_BR
dc.relation.ispartofEvidence-Based Complementary and Alternative Medicinept_BR
dc.subjectGastrocnemius muscleeng
dc.subjectElectroacupunctureeng
dc.subjectHyperalgesiaeng
dc.subjectAcidic saline modeleng
dc.titleElectroacupuncture reduces hyperalgesia after injections of acidic saline in ratspt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)pt_BR
dc.description.resumoInjections of acidic saline into the gastrocnemius muscle in rats produce a bilateral long-lasting hyperalgesia similarto fibromyalgia in humans. No previous study investigated the effect of electroacupuncture (EA) on this acidic saline model. Thisstudy aimed to identify the effects of EA in the hyperalgesia produced by repeated intramuscular injections of acidic saline. Methods.Rats were divided into four groups (n = 6, each group): control, acupuncture, EA 15 Hz, and 100 Hz. Left gastrocnemius musclewas injected with 100 uL of pH 4.0 sterile saline twice five days apart. EA, acupuncture, or control therapy was daily administered(20 min) for 5 consecutive days under anesthesia. Needles were placed in the St36 and Sp6 acupoints. The assessment of secondarymechanical hyperalgesia, thermal hyperalgesia, and motor performance was performed before injections and before and after thetreatment performed on each day. The paw withdrawal threshold was tested using the nonparametric Kruskal-Wallis test anddifferences within the group Wilcoxon Matched Pairs. The latency and motor performance were tested for ANOVA parametrictest for independent measures, and for differences in the group, we used t-test for paired samples. Post hoc Tukey test was used formultiple corrections. p values less than 0.05 were considered statistically significant. Results. Indicate that there was a significantreduction of mechanical withdrawal threshold and paw withdrawal latency 24 hours following the second injection. Moreover,mechanical and thermal hyperalgesia were significantly reversed by EA 15, 100 Hz, and acupuncture. Conclusions. The results suggestthat EA high and low frequency as well as acupuncture are effective in reducing hyperalgesia in chronic muscle pain model.pt_BR
dc.description.localNew Yorkpt_BR
dc.identifier.doihttps://doi.org/10.1155/2014/485043-
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