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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/24564
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dc.contributor.authorQueiroz, João Carlos C.-
dc.contributor.authorAntoniolli, Ângelo Roberto-
dc.contributor.authorQuintans Júnior, Lucindo José-
dc.contributor.authorBrito, Renan Guedes de-
dc.contributor.authorBarreto, Rosana de Souza Siqueira-
dc.contributor.authorCosta, Emmanoel Vilaça-
dc.contributor.authorSilva, Thanany Brasil da-
dc.contributor.authorPrata, Ana Paula Nascimento-
dc.contributor.authorde Lucca Júnior, Waldecy-
dc.contributor.authorAlmeida, Jackson Roberto Guedes da Silva-
dc.contributor.authorLima, Julianeli Tolentino de-
dc.contributor.authorQuintans, Jullyana de Souza Siqueira-
dc.date.accessioned2026-02-10T18:56:30Z-
dc.date.available2026-02-10T18:56:30Z-
dc.date.issued2014-
dc.identifier.citationQUEIROZ, J. C. C. et al. Evaluation of the anti-Inflammatory and antinociceptive effects of the essential oil from leaves of Xylopia laevigata in experimental models. The Scientific World Journal, New York, n. 1, 2014. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2014/816450. Acesso em: 10 fev. 2026.pt_BR
dc.identifier.issn1537-744X-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/24564-
dc.languageporpt_BR
dc.subjectXylopia laevigataeng
dc.subjectAnti-inflammatory effectseng
dc.subjectEssential oileng
dc.titleEvaluation of the anti-Inflammatory and antinociceptive effects of the essential oil from leaves of Xylopia laevigata in experimental modelspt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)pt_BR
dc.description.resumoXylopia laevigata (Annonaceae) is a medicinal plant used in folk medicine to treat pain and inflammation. Thus, we investigated the possible antioxidant, antinociceptive, and anti-inflammatory effects of X. laevigata leaf essential oil (EOX) in animal models.Our EOX sample showed the presence of y-muurolene (17.78%), &-cadinene (12.23%), bicyclogermacrene (7.77%), and a-copaene(7.17%) as main compounds. EOX presented a strong antioxidant potential according to the DPPH, TBARS, and nitrite productiontests. Additionally, pretreatment with EOX, in mice, also significantly produced (p < 0.05 or p < 0.001) antinociceptive effect byreduction of nociceptive behavior (in formalin and writhing tests). The EOX showed c-Fos label in the olfactory bulb, piriformcortex, and periaqueductal gray. Acute administration of EOX exhibited a significant (p < 0.01 or p < 0.001) anti-inflammatoryprofile in the carrageenan-induced peritonitis and by the carrageenan-induced hindpaw edema tests in mice. Our results provideevidence for the use of X. laevigata by traditional medicine practitioners in the management of pain and inflammatory disorders.pt_BR
dc.description.localNew Yorkpt_BR
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