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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/24642
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dc.contributor.authorWhite, Pollyanna Alves Secundo-
dc.contributor.authorOliveira, Rita de Cássia Meneses-
dc.contributor.authorOliveira, Aldeidia Pereira de-
dc.contributor.authorSerafini, Mairim Russo-
dc.contributor.authorAraújo, Adriano Antunes de Souza-
dc.contributor.authorGelain, Daniel Pens-
dc.contributor.authorMoreira, José Cláudio Fonseca-
dc.contributor.authorAlmeida, Jackson Roberto Guedes da Silva-
dc.contributor.authorQuintans, Jullyana de Souza Siqueira-
dc.contributor.authorQuintans Júnior, Lucindo José-
dc.contributor.authorSantos, Márcio Roberto Viana dos-
dc.date.accessioned2026-02-25T18:41:40Z-
dc.date.available2026-02-25T18:41:40Z-
dc.date.issued2014-
dc.identifier.citationWHITE, P. A. S. et al. Antioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic review. Molecules, Basel, v. 19, n. 9, p. 14496–14527, 2014. Disponível em: https://www.mdpi.com/1420-3049/19/9/14496. Acesso em: 25 fev. 2026.pt_BR
dc.identifier.issn1420-3049-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/24642-
dc.languageengpt_BR
dc.publisherMDPIpt_BR
dc.relation.ispartofMoleculespt_BR
dc.subjectLichenseng
dc.subjectAntioxidantseng
dc.subjectAntioxidant response elementseng
dc.subjectDPPHeng
dc.subjectCancereng
dc.subjectChronic diseaseeng
dc.titleAntioxidant activity and mechanisms of action of natural compounds isolated from lichens: a systematic reviewpt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)pt_BR
dc.description.resumoChronic diseases such as cancer, diabetes, neurodegenerative and cardiovascular diseases are characterized by an enhanced state of oxidative stress, which may result from the overproduction of reactive species and/or a decrease in antioxidant defenses. The search for new chemical entities with antioxidant profile is still thus an emerging field on ongoing interest. Due to the lack of reviews concerning the antioxidant activity of lichen-derived natural compounds, we performed a review of the antioxidant potential and mechanisms of action of natural compounds isolated from lichens. The search terms “lichens”, “antioxidants” and “antioxidant response elements” were used to retrieve articles in LILACS, PubMed and Web of Science published until February 2014. From a total of 319 articles surveyed, 32 met the established inclusion and exclusion criteria. It was observed that the most common isolated compound studied was usnic acid, cited in 14 out of the 32 articles. The most often described antioxidant assays for the study of in vitro antioxidant activity were mainly DPPH, LPO and SOD. The most suggested mechanisms of action were scavenging of reactive species, enzymatic activation and inhibition of iNOS. Thus, compounds isolated from lichens are possible candidates for the management of oxidative stress, and may be useful in the treatment of chronic diseases.pt_BR
dc.description.localBaselpt_BR
dc.identifier.doihttps://doi.org/10.3390/molecules190914496-
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