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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/25203
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dc.contributor.authorDantas, Milla Gabriela Belarmino-
dc.contributor.authorReis, Silvio Alan Gonçalves Bomfim-
dc.contributor.authorDamasceno, Camila Mahara Dias-
dc.contributor.authorRolim, Larissa Araújo-
dc.contributor.authorRolim Neto, Pedro José-
dc.contributor.authorCarvalho, Ferdinando Oliveira-
dc.contributor.authorQuintans Júnior, Lucindo José-
dc.date.accessioned2026-07-06T19:13:23Z-
dc.date.available2026-07-06T19:13:23Z-
dc.date.issued2016-
dc.identifier.citationDANTAS, M. G. B. et al. Development and evaluation of stability ofa gel formulation containing the monoterpene borneol. The Scientific World Journal, New York, n. 1, 2016. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2016/7394685. Acesso em: 3 jun. 2025.pt_BR
dc.identifier.issn1537-744X-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/25203-
dc.languageengpt_BR
dc.relation.ispartofThe Scientific World Journalpt_BR
dc.subjectBorneoleng
dc.subjectMonoterpenoid alcoholeng
dc.subjectGel formulationeng
dc.titleDevelopment and evaluation of stability ofa gel formulation containing the monoterpene borneolpt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 4.0 Internacional (CC BY 4.0)pt_BR
dc.description.resumoBorneol is a bicyclic monoterpenoid alcohol commonly used in traditional Chinese and Indian medicine. It is extracted from theessential oil of various medicinal plants. It has antibacterial, analgesic, and anti-inflammatory action proven in studies that used oraland intraperitoneal applications of this monoterpene in mice. The current study was designed to develop a topical gel formulationcontaining the monoterpene borneol using carbopol as gel base and to evaluate its stability. The prepared formulation was subjectedto physical characterization and physical-chemistry assessment. The gel was prepared from carbopol and 5% of borneol. Theprepared gel was subjected to pharmacotechnical tests such as its pH, viscosity, conductivity, spreadability, centrifugation, andaccelerated stability with freezing-thaw cycle. The borneol was successfully incorporated into the carbopol formulation. Borneolgel (BG5) showed good stability after eight months of its development and after 12 days in the freeze-thaw cycle, not showingstatistical difference in pH value, conductivity, and viscosity before and after test. Furthermore, the formulation showed a goodspreadability. Therefore, it was concluded that the formulation could be very promising alternative for the topical or transdermaltreatment of skin diseases.pt_BR
dc.description.localNew Yorkpt_BR
dc.identifier.doihttps://doi.org/10.1155/2016/7394685-
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