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Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/25538
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dc.contributor.authorMatos, Diana Melo de-
dc.contributor.authorRamalho, Roberto J. R.-
dc.contributor.authorCarvalho, Bruno M.-
dc.contributor.authorAlmeida, Maria Augusta C. T.-
dc.contributor.authorPassos, Luciana F. D.-
dc.contributor.authorVasconcelos, Talmay Tavares Santos-
dc.contributor.authorMelo, Enaldo Vieira de-
dc.contributor.authorOliveira, Carla Raquel Pereira-
dc.contributor.authorSantos, Elenilde Gomes-
dc.contributor.authorRezende, Karla Freire-
dc.contributor.authorOliveira, Manuel Hermínio de Aguiar-
dc.date.accessioned2026-07-14T18:49:40Z-
dc.date.available2026-07-14T18:49:40Z-
dc.date.issued2016-
dc.identifier.citationMATOS, D. M. et al. Evolution to permanent or transient conditions in children with positive neonatal TSH screening tests in Sergipe, Brazil. Archives of Endocrinology and Metabolism, São Paulo, v. 60, n. 5, p. 450–456, 2016. Disponível em: https://www.scielo.br/j/aem/a/CJHhtpD7RrZ5wBPfSRqRXLd/?lang=en. Acesso em: 14 jul. 2026.pt_BR
dc.identifier.issn2359-4292-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/25538-
dc.languageengpt_BR
dc.publisherSociedade Brasileira de Endocrinologia e Metabologiapt_BR
dc.relation.ispartofArchives of Endocrinology and Metabolismpt_BR
dc.subjectNeonatal screeningeng
dc.subjectCongenital hypothyroidismeng
dc.subjectThyrotropineng
dc.subjectThyroid hormoneseng
dc.titleEvolution to permanent or transient conditions in children with positive neonatal TSH screening tests in Sergipe, Brazilpt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição 4.0 Internacional (CC BY 4.0)pt_BR
dc.description.resumoObjectives: To assess the evolution to permanent or transient conditions in children with positive neonatal TSH tests in Sergipe, Brazil, from 2004 to 2010. Subjects and methods: Out of 193,794 screened newborns, 713 presented a neonatal TSH level higher than the local cutoff (5.2 µU/mL). From the confirmatory serum TSH values, the children were diagnosed with initial congenital hypothyroidism (CH) or suspect CH. From the evolution, they were classified as permanent CH, hyperthyrotropinemia, or transient TSH elevation. The mean incidence of each final condition was calculated for the total period of time. Results: The initial diagnosis included 37 CH (18.1%) and 167 suspect CH (81.9%) cases. The final diagnosis included 46 cases of permanent CH (22.5%), 56 of hyperthyrotropinemia (27.5%), and 102 of transient TSH elevation (50.0%). Out of the 37 cases of initial CH, 23 (62.2%) had permanent CH, nine (24.3%) had hyperthyrotropinemia, and five (13.5%) had transient TSH elevation. Out of the 167 suspect CH cases, 23 (13.8%) had permanent CH, 47 (28.1%) had hyperthyrotropinemia and 97 (58.1%) had transient TSH elevation. The mean incidence after the follow up was 1:4,166 for permanent CH, 1:3,448 for hyperthyrotropinemia, and 1:1,887 for transient TSH elevation. Eighty-six percent of the children with an initial diagnosis of CH and 41.9% with suspect CH had a permanent condition (CH or hyperthyrotropinemia). Conclusions: The follow-up of children with an initial diagnosis of CH or suspect CH is necessary to determine whether the disorder is permanent because predicting the evolution of the condition is difficult.pt_BR
dc.description.localSão Paulopt_BR
dc.identifier.doihttps://doi.org/10.1590/2359-3997000000189-
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