Use este identificador para citar ou linkar para este item: http://ri.ufs.br/jspui/handle/riufs/937
Tipo de Documento: Artigo
Título: Effect of periodontal therapy on metabolic control and levels of IL-6 in the gingival crevicular fluid in type 2 diabetes mellitus
Autor(es): Camargo, Gabriela Alessandra da Cruz Galhardo
Lima, Meyriane de Andrade
Fortes, Tânia Vieira
Souza, Cristiane Salgado de
Jesus, Amélia Maria Ribeiro de
Almeida, Roque Pacheco de
Data do documento: Jul-2013
Abstract: Background: The aim of this study was to compare the efficacy of metabolic control and levels of interleukin 6 (IL-6) in gingival crevicular fluid after periodontal therapy in type 2 diabetes mellitus (DM) and nondiabetic (NDM) patients. Methods: This study was performed in 20 subjects (10 type 2 DM and 10 NDM patients with generalized chronic periodontal disease. Both groups were recorded for clinical parameters (plaque index (PI), gingival index (GI), probing depth (PD), gingival recession (GR) and clinical attachment level (CAL)), metabolic control (fasting glucose levels, glycated a-hemoglobin (HbA1c), low-density lipoprotein (LDL), high-density lipoprotein (HDL), triglycerides (TR)), and IL-6 levels at baseline and 3 months after periodontal treatment. Results: DM and NDM patients revealed significant statistical reductions for clinical parameters (P < 0.05, RM ANOVA) after 3 months. DM group had improvements on HbA1c and had significant statistical increased of TRG (P < 0.05, RM ANOVA) after 3 months. No differences of LDL/HDL and IL-6 levels were found after 3 months in both groups. Conclusion: DM group presented a significant reduction of HbA1c levels after periodontal therapy. However, TRG levels increased after 3 months, which suggest more confirmatory studies to investigate if these results will be repeated in other studies.
Palavras-chave: Terapia periodontal
Diabetes mellitus tipo 2
Interleucina
Doença periodontal
ISSN: 1998-3603
Instituição/Editora: Medknow
Citação: CAMARGO, G. A. C. G. et al. Effect of periodontal therapy on metabolic control and levels of IL-6 in the gingival crevicular fluid in type 2 diabetes mellitus. Indian Journal of Dental Research, New Delhi, v. 24, n. 1, 2013. Disponível em: <http://www.ijdr.in/text.asp?2013/24/1/110/114953>. Acesso em: 21 fev. 2014.
Licença: Creative Commons Attribution 3.0 Unported License
URI: https://ri.ufs.br/handle/riufs/937
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