Comparativo do grau de fibrose hepática entre os gêneros masculino e feminino, antes e após a cirurgia bariátrica

Abstract

Objective: To compare the degree of liver fibrosis between male and female in the preoperative and postoperative bariatric surgery. Methods: To assess through NAFLD Fibrosis Score, which uses age, BMI, compared AST / ALT, albumin, platelet count and presence or absence of hyperglycemia. We used the analysis of variance (ANOVA) for repeated measures comparison between groups and times (preoperative and postoperative 06 and 12 months), an association between categorical variables we used Fisher test changes between times for variables categorical binomial was used Q Cocharam test. The significance level was 5%. Results: of the 59 patients 28.8% were group-M with a mean age 37.12 ± 12.4 years and 71.2% Group-F mean age of 38.5 ± 10.55 years. The average BMI in the groups were respectively 51.12 ± 14.59 kg / m² and 42.59 ± 8.35 kg / m² in the preoperative and postoperative 6, were 36.66 ± 9.1 kg / m² and 32.59 ± 7.06 kg / m²; postoperative 12, were 34.05 ± 9.73 kg / m² and 30.03 ± 7.73 kg / m², with a reduction in BMI in both NAFLD and for the F group (p <0.001). Preoperatively 4 (23.52%) in group-M had advanced liver fibrosis, progressing to 2 (11.76%) and F-6 group (14.28%) had advanced liver fibrosis preoperatively, They evolved to 4 (9.52%) after 12 months. Conclusion: The advanced NAFLD is associated with high BMI, and more male obese patients. Bariatric surgery is an important therapeutic option in both genders, and the correction of NAFLD, faster in women.