Manifestações pulmonares no lúpus eritematoso sistêmico

Abstract

Introduction: Systemic lupus erythematosus is a chronic inflamatory disease that affects multiple organs. Over 50% of lupus patients have pulmonary manifestations, however the diagnosis and treatment of these manifestations are a challenge, requiring an accurate understanding in order to improve the quality of life of patients. Objective: perform a systematic review to the literature on the presence of pulmonary comorbidities in individuals with Systemic Lupus Erythematosus. Method: exploratory and descriptive systematic review. Result: 77 articles were included in this systematic review. Of which: 40 (52%) case reports, 21 (27.2%) retrospective cohorts, 6 (7.8%) case-control studies, 4 (5.2%) case series, 4 (5.2%) ) prospective cohorts, 1 (1.3%) analytical cross-sectional study and 1 (1.3%) observational cross-sectional study. Conclusions: Presenting different degrees of severity, it is crucial to broaden the understanding of each pulmonary implication, aiming at early detection during the initial stages of the disease and, ideally, minimizing the accumulation of lesions. Research in this area is sparse and fragmented, which leads to a lack of a consistent evidence base to address most of these complications.