1. Repositório Institucional da Universidade Federal de Sergipe - RI/UFS
2. PRODUÇÃO CIENTÍFICA
3. DMO - Departamento de Morfologia
4. DMO - Artigos de periódicos

Tipo de Documento:	Artigo
Título:	Protective effect of a hydroethanolic extract from Bowdichia virgilioides on muscular damage andoxidative stress caused by strenuous resistance training in rats
Autor(es):	Santos, Jymmys Lopes dos Dantas, Rafaela Eugênia Arce Lima, Clésio Andrade Araújo, Silvan Silva de Almeida, Elis Cristiane Valença de Marçal, Anderson Carlos Estevam, Charles dos Santos
Data do documento:	2014
Resumo:	Background: Natural antioxidants can reduce oxidative damage caused by high-intensity resistance training (RT).We investigated the in vitro antioxidant potential of hydroethanolic extract (HEE) from Bowdichia virgilioides onmuscular damage and oxidative stress in rats subjected to high-intensity RT.Methods: Thirty-two male Wistar rats were divided into four experimental groups: 1) control group (CG), oraladministration (P.O.) of vehicle; 2) trained group (TG), vehicle-treated with RT; 3) B. virgilioides untrained group (BVG),treated with B. virgilioides HEE (200 mg/kg P.O.); and 4) trained B. virgilioides group (TBVG), treated with B. virgiliodesHEE (200 mg/kg P.O.). All animals were habituated to the training apparatus for 1 week. CT and TBVG animals weresubjected to the training protocol, which consisted of three sets of 10 repetitions with 75% of the load establishedusing the one-repetition maximum, for four weeks. CG and BVG animals were manipulated and fixed to theapparatus three times a week with no load. Treatment with B. virgilioides HEE or vehicle treatment was initiated after25 days of RT (5 days; one dose per day). At the end of the experiments, plasmatic and gastrocnemius samples fromall groups were obtained for the assessment of lipid peroxidation and creatine kinase activity.Results: Compared to TG rats, TBVG rats showed decreases in plasma and gastrocnemius tissue lipid peroxidationby 55.68% (p <0.0001) and 66.61% (p <0.0012), respectively. Further, compared to TG rats TBVG rats showeddecreases in plasma and gastrocnemius tissue oxidative stress by 62.83% (p <0.0005) and 54.97% (p <0.0197),respectively.Conclusions: B. virgilioides HEE treatment reduced markers of oxidative stress caused by high-intensity RT. Further,HEE treatment during training significantly reduced the markers of tissue damage.
Palavras-chave:	Oxidative stress Physical exercise Hydroethanolic extract
ISSN:	1550-2783
Parte de :	Journal of the International Society of Sports Nutrition
Idioma:	eng
Instituição/Editora:	Taylor & Francis
Citação:	SANTOS, J. L. et al. Protective effect of a hydroethanolic extract from Bowdichia virgilioides on muscular damage andoxidative stress caused by strenuous resistance training in rats. Journal of the International Society of Sports Nutrition, Philadelphia, v. 11, n. 58, 2014. Disponível em: https://www.tandfonline.com/doi/full/10.1186/s12970-014-0058-3#abstract. Acesso em: 21 jan. 2026.
Licença:	Creative Commons Atribuição 4.0 Internacional (CC BY 4.0)
URI:	https://ri.ufs.br/jspui/handle/riufs/24338
Aparece nas coleções:	DEF - Artigos de periódicos DFS - Artigos de periódicos DMO - Artigos de periódicos

Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.