1. Repositório Institucional da Universidade Federal de Sergipe - RI/UFS
  2. PRODUÇÃO CIENTÍFICA
  3. DESL - Departamento de Educação em Saúde
  4. DESL - Artigos de periódicos
Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/23868
Registro completo de metadados
Campo DCValorIdioma
dc.contributor.authorOliveira, Flávia Márcia-
dc.contributor.authorRuiz-de-Souza, Valéria-
dc.contributor.authorPereira, Maria Aparecida Campana-
dc.contributor.authorGontijo, Cristiano Machado-
dc.date.accessioned2025-11-17T19:11:40Z-
dc.date.available2025-11-17T19:11:40Z-
dc.date.issued2013-12-
dc.identifier.citationOLIVEIRA, F. M. et al. Expression of costimulatory molecules in antigen-activated peritoneal macrophages treated with either ovalbumin or palmitoyl-ova conjugates. Brazilian Archives of Biology and Technology, Curitiba, v. 56, n. 6, p. 962-970, nov./dez. 2013. Disponível em: https://www.scielo.br/j/babt/a/CbVKn5xKtwfXDsjVm5zrP3r/?lang=en. Acesso em: 17 nov. 2025.pt_BR
dc.identifier.issn1678-4324-
dc.identifier.urihttps://ri.ufs.br/jspui/handle/riufs/23868-
dc.languageengpt_BR
dc.publisherInstituto de Tecnologia do Paraná - Tecparpt_BR
dc.relation.ispartofBrazilian Archives of Biology and Technologypt_BR
dc.subjectOvalbumineng
dc.subjectPalmitic acideng
dc.subjectCellular immunityeng
dc.subjectCD86eng
dc.subjectCD80eng
dc.subjectCD11beng
dc.titleExpression of costimulatory molecules in antigen-activated peritoneal macrophages treated with either ovalbumin or palmitoyl-ova conjugatespt_BR
dc.typeArtigopt_BR
dc.identifier.licenseCreative Commons Atribuição-NãoComercial 4.0 Internacional (CC BY-NC 4.0)pt_BR
dc.description.resumoOne of the mechanisms by which adjuvants are believed to promote T-cell activation and prevent induction of oral tolerance is by up-regulating the expression of co-stimulatory molecules on antigen presenting cells. Mice treated orally with palmitoyl-ovalbumin conjugates become immunized, while those treated with native ovalbumin (Ova) become tolerant. Cells from the peritoneal cavity of B6D2F1 mice were cultured in the presence of 0.01, or 0.1 mg/100µl of either Ova, or palmitoyl-Ova and tested for the presence of cell markers. PE-conjugated anti-mouse CD80, CD86, and CD11b antibodies as well as biotin-PE were used to stain the antigen-activated peritoneal cells. A significant increase in the expression of CD86 and CD80 was observed following in vitro stimulation with palmitoyl-Ova; additionally, both Ova and palmitoyl-Ova induced the basal expression of CD11b. These findings could be related with the strong T-cell proliferative response induced by palmitoyl-Ova.pt_BR
dc.description.localCuritibapt_BR
Aparece nas coleções:DESL - Artigos de periódicos

Arquivos associados a este item:
Arquivo Descrição TamanhoFormato 
CostimulatoryMoleculesAntigenAtivatedPeritonealMacrophages.pdf135,45 kBAdobe PDFThumbnail
Visualizar/Abrir
Mostrar registro simples do item Visualizar estatísticas


Os itens no repositório estão protegidos por copyright, com todos os direitos reservados, salvo quando é indicado o contrário.