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Document Type: Artigo
Title: Volatile constituents and behavioral change induced by Cymbopogon winterianus leaf essential oil in rodents
Authors: Leite, Bárbara Lima Simioni
Souza, Thaís Teles de
Antoniolli, Ângelo Roberto
Guimarães, Adriana Gibara
Barreto, Rosana de Souza Siqueira
Quintans, Jullyana de Souza Siqueira
Bonjardim, Leonardo Rigoldi
Alves, Péricles Barreto
Blank, Arie Fitzgerald
Almeida, Jackson Roberto Guedes da Silva
Lima, Julianeli Tolentino de
Quintans-Júnior, Lucindo José
Araújo, Adriano Antunes de Souza
Issue Date: Aug-2011
Abstract: Cymbopogon winterianus Jowitt (‘Java citronella’) is an important essential oil yielding aromatic grass cultivated in India and Brazil and its volatile essential oils extracted from its leaves are used in perfumery, cosmetics, pharmaceuticals and flavoring industries. However, there is no report on any psychopharmacological study of C. winterianus leaf essential oil (LEO) available to date. In this study, the pharmacological effects of the LEO were investigated in animal models and its phytochemical analyses. GC-MS analysis showed a mixture of monoterpenes, as citronellal (36.19%), geraniol (32.82%) and citronellol (11.37%). LEO exhibited an inhibitory effect on the locomotor activity of mice, an antinociceptive effect by increasing the reaction time in the writhing and capsaicin tests. All doses induced a significant increase in the sleeping time of animals not having modified however, the latency. The LEO did not alter the remaining time of the animals on the rota-rod apparatus. These results suggest a possible central effect
Keywords: Cymbopogon winterianus
Óleos essenciais
ISSN: 1684-5315
Citation: LEITE, B. L. S. et al. Volatile constituents and behavioral change induced by Cymbopogon winterianus leaf essential oil in rodents. African Journal of Biotechnology, Nairobi, v. 10, n. 42, ago. 2011. Disponível em: <>. Acesso em: 7 jun. 2013.
License: Creative Commons Attribution License
Appears in Collections:DEA - Artigos de periódicos
DESL - Artigos de periódicos
DFA - Artigos de periódicos
DFS - Artigos de periódicos

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