Perfil clínico dos pacientes com esclerose sistêmica atendidos em hospital público universitário

Abstract

Introduction: Systemic Sclerosis is a progressive autoimune disease of the connective tissue, characterized by inflammatory, vascular and sclerotic changes of the skin and various organs. It has a range of clinical manifestations that vary among patients with the disease. Objective: To evaluate the clinical profile of patients diagnosed with systemic sclerosis treated at the University Hospital of Sergipe. Patients Methods: Retrospective study of 31 patients with Systemic Sclerosis followed at the Rheumatology Outpatient Clinic of Sergipe University Hospital for clinical manifestations such as: Raynaud, telangiectasia, leukomelanodermia, digital ulcers, dysphagia, gastroesophageal reflux, dyspnea, cough, pulmonary fibrosis, pericarditis, systemic arterial hypertension, pericardial effusion, scleroderma renal crisis, arthritis, athralgia. Results: We found a female predominance (80.65%), mean age of 50 years, mean age at diagnosis of 43.2 years, white color (22.58%). Everyone had skin involvement, 30 (96.77%) had gastrointestinal involvement, 29 (93.55%) had respiratory involvement, 22 (70.97%) had musculoskeletal involvement, 20 (64.62%) had cardiac involvement, 3 (9.68%) had renal involvement. No data on sexual function were found. No case was associated with malignancy and 11 (35.48%) patients presented overlap. Conclusion: Raynaud's phenomenon was more prevalent (93.55%) and was an initial manifestation of the disease in 72.41% of patients, thus being one of the main symptoms that allow early diagnosis. There was a high prevalence of medium / low dysphagia, gastroesophageal reflux, cough and dyspnea, symptoms that if identified in association with other specific signs, such as Raynaud, skin thickening and microstomy, may lead to an early diagnosis of the disease by the general practitioner