Use este identificador para citar ou linkar para este item: https://ri.ufs.br/jspui/handle/riufs/24352
Tipo de Documento: Artigo
Título: Morphological changes in the suprachiasmatic nucleus of aging female marmosets (Callithrix jacchus)
Autor(es): Engelberth, Rovena Clara Galvão Januário
Silva, Kayo Diogenes de Azevedo
Azevedo, Carolina Virginia Macêdo de
Gavioli, Elaine Cristina
Santos, José Ronaldo dos
Soares, Joacil Germano
Nascimento Júnior, Expedito Silva do
Cavalcante, Judney Cley
Costa, Miriam Stela Maris de Oliveira
Cavalcante, Jeferson de Souza
Data do documento: 2014
Resumo: The suprachiasmatic nuclei (SCN) are pointed to as the mammals central circadian pacemaker. Aged animals show internal timedisruption possibly caused by morphological and neurochemical changes in SCN components. Some studies reported changes ofneuronal cells and neuroglia in the SCN of rats and nonhuman primates during aging. The effects of senescence on morphologicalaspects in SCN are important for understanding some alterations in biological rhythms expression. Therefore, our aim was toperform a comparative study of the morphological aspects of SCN in adult and aged female marmoset. Morphometric analysis ofSCN was performed using Nissl staining, NeuN-IR, GFAP-IR, and CB-IR. A significant decrease in the SCN cells staining withNissl, NeuN, and CB were observed in aged female marmosets compared to adults, while a significant increase in glial cells wasfound in aged marmosets, thus suggesting compensatory process due to neuronal loss evoked by aging.
Palavras-chave: Suprachiasmatic nucleus
Callithrix jacchus
Morphological changes
Neurochemical changes
Callithrix jacchus
Marmosets
ISSN: 2314-6141
Parte de : BioMed Research International
Idioma: eng
Instituição/Editora: Hindawi Publishing Corporation
Citação: ENGELBERTH, R. C. G. J. et al. Morphological changes in the suprachiasmatic nucleus of aging female marmosets (Callithrix jacchus). BioMed Research International, New York, n. 1, 2014. Disponível em: https://onlinelibrary.wiley.com/doi/10.1155/2014/243825. Acesso em: 22 jan. 2026.
Licença: Creative Commons Atribuição 3.0 Não Adaptada (CC BY 3.0)
URI: https://ri.ufs.br/jspui/handle/riufs/24352
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